Advanced Molecular Detection and One Health

One Health Response to a Multidrug – Resistant (MDR) Salmonella Heidelberg Outbreak

Antibiotic resistance is a One Health problem best addressed with a One Health approach. One Health is an approach that recognizes the interconnectedness of the health of people, animals, and the environment. It involves collaboration across human and animal health, environment, and other relevant sectors. Antibiotic-resistant bacteria have developed the ability to defeat the drugs designed to kill them and are an important One Health issue. Today, advanced molecular detection technologies, such as whole genome sequencing (WGS), allow scientists to study how antibiotic resistance evolves and spreads. WGS also provides important information for responding to disease outbreaks. In a 2015–2018 outbreak of multidrug-resistant Salmonella Heidelberg, WGS revealed that the outbreak in people was connected to contact with dairy calves and calf environments.

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3 panels - 1st panel shows a sick calf and a child in a hospital bed, 2nd panel shows testing images, 3rd panel shows a farmer and vet with a cow